Posts

Your brace, an “accessory” that makes you unique

/0 Comments/in /by

Every era has its own fashion corset, you might say, if you think of the various ways, in which this particular garment has been used over the years.

First created in the sixteenth century, it has always been intended to enhance the female silhouette by the aesthetic canons of the times. Worn under clothes, it modified the shape of the body. It has undergone a continuous process of evolution to the point of becoming, nowadays, an actual item of clothing—a fashion garment that, again for aesthetic reasons, is deliberately left visible.

The well-known TV series Bridgerton, which features women in Regency-style corsets, has brought them back into vogue, so much so that, in the name of gender equality, male models are now even wearing them on catwalks. And, as we saw on the red carpet at the Oscars, corsets appeal both to Gen Z and over-60s celebrities, with Halle Bailey and Jamie Lee Curtis both appearing in Dolce & Gabbana ones.

Although the orthopaedic braces used in the rehabilitation treatment of scoliosis are created with a completely different function in mind, they, too, are worn to achieve a better silhouette. Indeed, one of their purposes is undoubtedly to improve the appearance of the patient’s back, as well as its health, of course.

Whenever we mention corrective braces, the initial response is always one of fear and dismay because the first image that springs to mind is that of some object that is impossible to disguise under clothes. We might think, for example, of the Milwaukee brace (now hardly ever used anywhere in the world), which even has a kind of chin rest that clearly can’t be concealed under clothing. However, thanks to research and continuous efforts to develop treatments that are the least invasive possible, the braces being produced nowadays are not only more and more effective as corrective devices, but also increasingly close-fitting and therefore impossible to see under clothes. One example is the Sforzesco brace, developed by ISICO, which is just as effective as casting.

Familiarity with these somewhat “awkward accessories” has grown in recent years as people are encouraged to regard them (whatever type they are) as objects that are just a part of everyday life and don’t need to be covered up. Actually, plastic braces now even exist that can be customized with different Thermo adhesive designs.

It’s a bit like the situation with glasses: frames have increasingly evolved, following fashion, and today the variety available is so great that there is something for all tastes, particularly eccentric styles. In this way, a person’s glasses are now a fundamental part of their style and identity. Their purely medical function has been combined with a strong aesthetic component, turning them into true accessories.

Similarly, dental braces have become increasingly customisable, and limb prosthetics, in part thanks to athletes, are now part of everyday life too. Indeed, many of those who wear them are happy to show them off as they are part of what makes them unique.

All these are examples of “awkward accessories” that are now a part of everyday life. And why shouldn’t this also be true of the corrective braces worn by young scoliosis patients?  

My next comments are aimed directly at those who wear braces or are about to start doing so.

Just like glasses, dental braces or limb prosthetics, a scoliosis brace should be seen, and treated, as something that sets you apart, but in a positive way, as something that is peculiar to you — something that makes you special, stronger and more self-confident, while also caring for your back. Although this might initially sound impossible, over time you really will come to see it as a strength.

You might think, “it’s easy for the physiotherapist to talk. They haven’t actually gone through this. We patients are the ones who have to wear these things, and only we can really know what it feels like.” 

Well, this is where, as a physiotherapist, I am able to draw on my own experience as a former patient. I lived with a brace for 7 years, wearing it full-time to begin with. And on the basis of that experience, I feel compelled to urge all youngsters who are embarking on, or about to embark on, this journey to use their brace and see it as a distinguishing feature, something to joke about with friends, something that makes you unique and will help you in your adult life (even though I realise that when you’re young it’s hard to think that far ahead).

Erica, former ISICO patient and now ISICO therapist

Isico Alliance, excellence in spine

/0 Comments/in /by

Isico’s goal has always been to promote the best therapies for the treatment of scoliosis in the world, and it is precisely from this idea and to give proper answers to the requests we periodically receive that we founded the Isico Alliance.

“ISICO stands alongside the ISICO Alliance Centres to support applying proper braces, organising new activities, and providing better care to their patients—explains Fabio Zaina, physiatrist and one of the project coordinators — taking advantage of the experience and ongoing innovations ISICO realises day by day. In fact, ISICO services mean excellent care for patients and an excellent approach for the centre.” 

There are several advantages from which an Isico Alliance centre can choose, from brace delivery, ISICO takes care of the entire production cycle of the prescribed brace in the workshops in Italy, to brace design, ISICO gives its assistance in designing the brace that will be produced on-site, from the training of a local orthotist to equip them with the skills necessary to manage the entire process of SPoRT (Symmetric, Patient-oriented, Rigid, Three-dimensional, active) braces production, to the opportunity to organise periodically SEAS courses in the local area, up to the use of the best technology for best care thanks to ScoliosisManager, the software developed by ISICO providing a uniform data collection protocol. Other optional services available are the ISICO iOS-Android app featuring specific functions for patients and ISICO practitioners, and Telemedicine services delivered to local patients directly by ISICO for complex or particular cases.

Do you wish to join the Alliance, or do you want to ask for more information? Please visit the website: https://isicoalliance.com

Margherita, sport, and scoliosis: a possible pairing

/0 Comments/in /by

What distinguishes ISICO in the treatment of scoliosis is a therapeutic approach that allows you to combine treatment with exercises and brace with sporting passions, even high-level competitive ones. This happened to Margherita, 14 years old, from the Marche region in Italy, who is an aerobic gymnastics champion.
We asked our young patient to share her experience while she prepares for an important sporting event: the Aerobic Gymnastics World Championships, scheduled for Pesaro, Italy, in September. Let’s discover with her how it is possible to reconcile sport and a brace.

How did your passion for aerobic gymnastics arise? 
It all started as a game with physical gymnastics. I was only 4 years old. Then my coach suggested the aerobics course to me, and from then on I became passionate about this sport.

When were you diagnosed with scoliosis?
I was 8 years old, it was in 2018…

What has been the impact of scoliosis on your daily life, at school and with friends?
At the beginning, I was monitored periodically and did specific exercises with my physiotherapists, who were special people for me, helping me to understand my condition better. As I grew up, my curve got worse, so I started the journey with ISICO and I found myself very well.

Do you wear a brace? For how many hours a day?
I started wearing the brace one year ago; it wasn’t easy because initially I had to wear it 20 hours a day; after a few months, it was decreased to 18 hours.

How do you reconcile the brace with sporting activity? How many hours do you train?
When I wore the brace for 20 hours, I only took it off for workouts. Now, my ISICO physiatrist, Fabio Zaina, has reduced the hours I wear it. I generally train between three and four hours a day, six days a week. In the summer, however, the hours increase. There are also double workouts.

What would you recommend to a peer who is starting corset therapy and playing sports?
Sport, like brace wearing, requires consistency, continuity, and tenacity. The first few weeks in a brace are not easy, but then everything improves, and you get used to it. My back has improved, and that’s the most important thing.


What are your next goals and competitions?
During this period, I am training for the World Championships, which will be held in Pesaro, Italy, in September.

Good luck, Margherita!

We remind you that ISICO’s innovative approach includes:

•  SEAS: specific exercises for scoliosis

•  Personalized Therapy: each patient receives a tailor-made treatment plan, which takes into account specific individual needs and conditions

•  Multidisciplinary Approach: the therapeutic team consists of physiotherapists, spine specialists and orthotist, who work together to offer a complete physical and psychological approach to treating scoliosis.

Sanders staging: the pros and cons?

/0 Comments/in /by

The progression of idiopathic scoliosis is related to skeletal growth, peaking during the adolescent growth spurt. Subsequently, once skeletal maturity has been reached, the pathology usually stabilises or slows down.

Knowing the predictors of skeletal maturity allows physicians to predict the risk and timing of curve progression, and therefore choose the most suitable treatment for their patient’s scoliosis.

Several indicators of skeletal maturity are closely linked to the progression of scoliosis. They include chronological age, height and weight, development of secondary sexual characteristics, and menarche.
However, skeletal maturity is known to be the most sensitive indicator of both the speed of skeletal growth and its completion. (1)

Numerous staging systems for evaluating skeletal maturity, in addition to the Risser sign, have been developed and used in patients with scoliosis. In the scientific community, particularly in the USA, the Sanders staging system is becoming increasingly popular.

Unlike the Risser method, which evaluates the degree of ossification of the iliac crests, the Sanders approach is based on the assessment of the ossification of the epiphyses of the wrist and hand bones, and it divides bone growth into 8 stages. Stage 3 corresponds to the pubertal growth peak when the risk of scoliosis worsening is greatest, while stage 8 corresponds to full skeletal maturity, and thus to the absence of a risk of worsening (in the case of curves measuring less than 50°) (2).

So, what are the pros and cons of this method of assessing skeletal maturity?

PROS:

1. It accurately predicts the skeletal growth peak: the Sanders classification system offers the possibility of dividing the relevant growth periods of patients who are still skeletally immature into multiple categories and would all be grouped as stage 0 using the Risser system. Essentially, some Risser stage 0 patients are at higher risk and more developmentally immature than others who are more skeletally mature but still classified as Risser 0 (1). 

2. It more reliably predicts residual growth: the Sanders classification can help doctors to predict residual growth in scoliosis patients more accurately than is possible with other assessment methods, and this allows them to plan better treatment (such as when to “wean” patients off their braces) and better monitor the evolution of the disease. (1)

3. It is a support tool: like other methods, the Sanders staging system, combined with clinical and radiographic parameters, allows doctors to make more informed decisions on the treatment of scoliosis, such as the decision to opt for a conservative approach (based on specific physiotherapeutic exercises and bracing) as opposed surgery, and vice versa (3).

CONS:

1. Its ability to predict skeletal growth may be limited: the Sanders staging system estimates skeletal maturity and residual growth, but it is not 100% accurate and may be limited in its ability to predict this type of growth.

2. It involves radiation exposure: to perform Sanders staging, radiographs have to be taken of the wrist, but this would mean increasing the radiation exposure of young patients, an aspect we always pay close attention to, and something we try to avoid as much as possible. as much as possible. In some places they experimented performing the classical spinal x-rays with specific hand positions to be able to see also the Sanders, but this is still experimental, and we don’t know yet if and how it changes the spinal posture. It could be a solution. In fact, we recommend that our patients have X-rays taken using EOS, a tool that allows their radiation exposure to be reduced. Of course, modern X-rays are nothing like the X-rays of the past, but it is nevertheless always better to have as few as possible.

3. Issues of cost and availability of resources: Sanders staging requires radiographic/logistical resources and specific expertise to interpret the images, which may not always be available in all healthcare settings. Furthermore, using the Sanders system can result in additional costs for patients or for the healthcare system.

Finally, our scientific director, Prof. Stefano Negrini, has explained an important reason why Sanders staging is not currently used at Isico: “We have a very pragmatic approach to the problem, that is based on adding further radiation only if necessary and if it would change our clinical behaviour. The reality is that scoliosis is still highly unpredictable: it can progress unexpectedly at any bone staging or it can stay stable at the highest risk phases. Consequently, the only clinical change when we are at a high-risk phase is seeing the patients more often, and intervening if needed because of progression. Would that change with more precise knowledge of bone maturity? Bone age is correlated with the risk, but not precise enough to rely on that alone – there are too many other unknowns… To explain all this, I often tell my patients that scoliosis treatment is rather like driving a car on a foggy night. We have some significant landmarks, but we never know exactly where we are. Increasing the precision of external reference points may perhaps help us, but it does not take away the fog or the night, which are the two factors that most determine our risk of having an accident, more than the road signs. In other words, we might well manage to obtain a more accurate assessment of the patient’s skeletal growth. Still, if the disease ends up following this indication only partially and behaving in a way we can’t control, then in reality we have not actually obtained any extra information that is really useful for treating our patient. For this reason, we don’t ask patients to have an additional X-ray if it is not really going to change their treatment significantly”.

References

1 – Prediction of Curve Progression in Idiopathic Scoliosis

2 – Maturity Indicators and Adolescent Idiopathic Scoliosis: Evaluation of the Sanders Maturity Scale

3 – Managing the Pediatric Spine: Growth Assessment

ISSLS Milan: a success with 500 participants

/0 Comments/in /by

“It was a bit as if the world, that of research and clinics in the field of spinal pathologies, had gathered in Milan — this is the comment of Dr. Greta Jurenaite, physiatrist specialist at ISICO — on her first participation in the ISSLS international conference, held between the end of May and the beginning of June. The congress was huge, with around 500 participants, most foreigners, coming from everywhere from Japan to Australia to South America. The few Italians were mostly from our institute.”

We would like to remind you that on the occasion of the conference, the 50th anniversary of its foundation was also celebrated, and Prof. Stefano Negrini, ISICO scientific director, and Dr. Fabio Zaina, physiatrist at ISICO, acted as local guests.

Dr. Jurenaite continues: “The days often began at 7:30 and the presentations continued until dinner, a commitment that makes us understand how much new there is in this sector and how essential it is to keep up to date. I’ll give you an example. On the last day, we participated in a session dedicated exclusively to rehabilitation before back surgery. It was a moment of discussion and comparison, and we reflected on what is still missing to “educate and make the patient as aware as possible, concluding that it is necessary to provide as much information as possible. This is what we do at ISICO when we dedicate time to explaining what scoliosis is, the therapy steps, and the objectives, because every therapeutic choice must be shared with the patient. The discussion was so interesting that we proposed the topic as the subject of a possible scientific article, whose co-authors could be some of us ISICO doctors.” 

Green June: Arianna, a karate champion

/0 Comments/in /by

Since I was a child, I have always loved sports, so much so that I started practising karate at the age of 4. I certainly never imagined that just three years later I would find myself facing something bigger than myself: scoliosis.

I remember very well the first day I wore the brace; I wasn’t sad, I was just very confused. Initially, wearing a corset at school and in the gym didn’t bother me, but as I grew up, I started to feel the weight of other people’s judgement. Going to karate classes with a brace became increasingly difficult, especially because I felt limited and unable to give my all.

Despite this, my passion for karate was stronger than anything else, and despite being a child, I didn’t let scoliosis get me down.

The first satisfaction came from agonism competitions: at 12 years old, I won my first title as an Italian Karate champion, and, from that moment on, my motivation to train grew more and more. Shortly afterwards, however, as I entered adolescence, I began to feel embarrassed about having to wear the brace. I fell into a period of sadness that I couldn’t overcome: the races were going badly, and so was my mood. I got out of it thanks to my family and my karate teacher, who always supported me.

Karate was the strongest motivation that helped me overcome these difficulties and allowed me (and still allows me) to express myself. Once I got over that dark moment, I started winning again, but above all, I had fun during training and races. The results, in fact, did not take long to arrive, so much so that I won two more Italian championships in 2022 and 2024.

After seven years of sacrifices and sometimes difficult moments, my scoliosis has taught me how essential it is to get involved in life, not give up in the face of difficulties, and be tenacious and determined to achieve small and large goals.

Even if the path is not at all easy, I want to tell all the kids who, like me, are “braced” to never give up on their dreams.

I sincerely thank ISICO and, in particular, Dr. Zaina and my physiotherapist, Lorenza Vallini, who have taken care of me over the years. With their attention and professionalism, together with my sacrifices, today I can say that I am proud of my back.

Green June: Gaia, an artistic gymnastics champion

/0 Comments/in /by

Often, a diagnosis of scoliosis leads to despair and the fear of not being able to live one’s daily life as a “braced.” It is not so.
We don’t want to say that it is easy or doesn’t require many sacrifices, but that despite the brace or wearing it, you can continue, for example, to practice sports. Even at a high competitive level, even with champion results, as in the case of the three stories we offer you this month dedicated to scoliosis.

Will you also wear green in June and share it with the hashtag #weargreenforscoliosis!

Gaia, a passion for artistic gymnastics
In November 2023, Gaia was diagnosed with scoliosis with primary right thoracic and left thoracic lumbar curves. A diagnosis that sounds like a condemnation of her passions. In fact, Gaia loves sports; she is very competitive and has been practicing artistic gymnastics since she was 5 years old. She trains for several hours, three times a week.
There’s no denying that her first thought was: Will I be able to practice gymnastics again? Will I be able to keep my habits the same? At the ISICO Centre, where she is being treated, the doctor who looks after her reassures her, telling her that she shouldn’t have to give up anything, especially gymnastics.

So it was: she continued to practice gymnastics, wearing her now faithful friend for 20 hours a day and training in the 4 hours of freedom, so much so that she won gold on the balance beam and placed second on the trampoline and third on floor exercise. “Our doctor was right—says Gaia—nothing has changed; sports, friends, habits… determination, perseverance, and sacrifice are needed, and, in a few years, I will be able to enjoy a healthy back, better posture, and bearing without having to give up my passions at the same time!”.

Modular Italian Brace works just as well as the Sforzesco

/0 Comments/in , /by

A modular brace that has the same practicality and comfort of wearing and the same proven effectiveness, even on the most severe curves, of the Sforzesco corset but with significantly reduced costs. It is the Modular Italian Brace (MIB), the latest corset developed by our institute, after the Sforzesco and the Sforzesco Free Plevis.
Its effectiveness is demonstrated by the data of one of our studies recently published in the Journal of Clinical Medicine, The New Modular Sforzesco Brace (Modular Italian Brace) Is as Effective as the Classical One: A Retrospective Controlled Study from a Prospective Cohort. “A research of considerable importance,” comments Dr. Francesco Negrini, physiatrist and author of the study. “We recently developed a new Sforzesco brace based on modularity (the Modular Italian Brace—MI brace) that could allow standardisation, facilitating global expertise diffusion, increased modifiability and adaptability, and cost savings due to longer brace life”.

We remind you that the Sforzesco brace is a very rigid push-up brace effective in adolescent idiopathic scoliosis (AIS), which revolutionised rehabilitation treatment years ago by replacing the cast but guaranteeing the same results. Recently, the “Free Pelvis” (FP) innovation has been introduced. It consists of semi-rigid material on the pelvis connected to the main rigid body of the brace on the trunk.
It was found that it does not change the in-brace and short-term results of classical very rigid braces and, consequently, can be safely applied.

The MI brace, even if built in a different way, keeps the main characteristic of the Sf brace, that is, the overall symmetry (with some asymmetries inserted in specific areas). In fact, it is the symmetry that allowed the development of the MI brace, where it is possible to recreate the asymmetrical needs of the SF brace through internal pads.

The MIB can be built and fully personalised directly for the patient, modifying the classical procedures of brace construction through CAD-CAM or casting. Moreover, the MIB can be continuously adapted during treatment, giving full adaptability to the patient during changes due to growth or treatment.

The MIB is an evolution of the SF-FP. The two braces share the semi-rigid material on the pelvis, a novelty that improves comfort and patient acceptability. On the other hand, Sf FP is built in a more traditional way, without the MIB modularity and the possibility to adapt the brace during treatment. With Sf FP, if the patient changes due to growth, the brace must be changed altogether.

“The braces considered in this paper share the same action; the question is if they also share the same results. We aimed to compare the short-term results of the two braces,” explains Dr. Negrini. “We compared in this retrospective study 231 patients with scoliosis, between 10 and 16 years old, 53 treated with a MI brace, and 178 treated with a Sforzesco brace. Both braces reduced the Cobb angle (−6◦ out-of-brace; −16◦ in-brace) without differences between groups. The results of the present study suggest that the SfB and MIB can have similar positive short-term results on moderate-to-moderate, moderate-to-severe, and severe curve brace treatment with modular braces. that could lead to easier diffusion worldwide, even where there are reduced economic means and expertise in brace treatment. Before suggesting a generalised use of the MIB as a first-line rigid brace treatment, the results should be confirmed in studies with longer follow-ups”.

SOSORT 2024 : presented studies, news and comments

/0 Comments/in /by

“This 2024 edition of the annual SOSORT conference, held in Boston, was also an opportunity for discussion, involvement, and growth. Every year, the level of research presented at SOSORT continues to rise, and we at ISICO are always at the forefront, commented Professor Stefano Negrini, Scientific Director of our Institute. SOSORT is undoubtedly the congress that brings together the most important specialists and the most significant research at an international level on the rehabilitation treatment of scoliosis. There was lots of news and great satisfaction for our specialists, who enlivened the conference with nine research projects presented both with posters and oral presentations. Dr. Fabio Zaina presented a study on the ability of the ODI and the SRS 22 to distinguish adult patients with or without scoliosis. At the moment, neither of the two questionnaires is able to make the distinction; in the ODI, subjects with scoliosis have greater difficulty lifting weights and standing compared to those who don’t have it, but the difference is not significant. Our physiotherapy director, Michele Romano, led two ongoing studies on curves; instead, our physiotherapist, Alessandra Negrini, in addition to animating the pre-conference by talking about Telemedicine, presented a review study on sagittal measurements among healthy children and adults, up to 40 years of age, to collect and, if possible, arrive at an average overall data measurement of kyphosis, lordosis, and other sagittal parameters.

“I myself presented two studies on adherence to brace treatment measured with sensors: one is a review study that demonstrated that both the use of sensors and counselling, i.e., the support given to patients during the course of treatment, can increase adherence to therapy, while the second study identified sex and age as the main variables that influence patient compliance,” explains Prof. Negrini.

There are also three posters signed by ISICO. Dr. Greta Jurenaite has prepared a poster on a case report of patients with lumbar Scheuermann, which demonstrates that exercises and a corset can effectively treat the pain caused by this pathology and that the brace also improves spinal growth by reducing the deformity. Dr. Giulia Fregna instead presented a review in the field of trunk neurophysiology in a poster; finally, the European Prepare project was also discussed with a poster by Dr. Carlotte Kiekens, already present at other SOSORT conferences but at her first as an ISICO specialist with her own research. “The congress was really interesting and informative! We were pleased to note that the PREPARE poster attracted a lot of attention – comments Dr. Kiekens – I was surprised that many professionals still do not have a clear understanding of the fact that rehabilitation treatment requires a multi-professional approach, involving the patient in a collaborative process and including diverse components such as brace therapy, exercises, cognitive behavioural therapy (CBT), psychological support, education, and much more. ISICO stands out for its advanced approach in this field.”. As introduced by Dr. Kiekens, there has been much discussion about artificial intelligence and its applications in the assessment of scoliosis, the development of therapeutic strategies, and the prediction of treatment outcomes, added Professor Negrini. Our participation in the PREPARE project positions us at the forefront of these new applications, thanks to our constant commitment to research, which is fundamental for the improvement of therapies. To the specialists present in Boston, we must add those who worked on this research, from therapists Bruno Lionelli, Serena Quaggio, and Sara Rossi Raccagni to Dr. Giulia Fregna. Finally, a moment from the conference that we are pleased to share: the appointment of Dr. Sabrina Donzelli, part of the ISICO staff for many years, as SOSORT president for the next two years. The first woman in the history of this society: congratulations to Dr. Donzelli, a great professional.

 We look forward to seeing you again at SOSORT 2025 in Dubrovnik!

Leaving for Boston

/0 Comments/in /by

In a few days, our specialists will attend the international annual SOSORT conference, which will be held in Boston, USA, from May 1 to 4 (please visit the website to register for the event or to learn more about it).  

ISICO will present a remarkable number of nine abstracts during the conference, two of which are Personal and Clinical Determinants of Brace-Wearing Time in Adolescents with Idiopathic Scoliosis and Influence of Specific Interventions on Bracing Compliance in Adolescents with Idiopathic Scoliosis — A Systematic Review of Papers Including Sensors’ Monitoring.

Both abstracts focus attention on the treatment of idiopathic scoliosis with braces, the factors that determine patient compliance, and its objective measurement. Bracing is, in fact, an effective treatment for medium-degree curves, and thermal sensors help monitor patients’ adherence (compliance), a critical issue in bracing treatment.  

Influence of Specific Interventions on Bracing Compliance in Adolescents with Idiopathic Scoliosis—A Systematic Review of Papers Including Sensors’ Monitoring underlines that high adherence to brace prescription is fundamental to gaining the maximum benefit from adolescent idiopathic scoliosis (AIS) treatment approach. Having an objective measure of compliance provided by the sensors allows the clinician to make informed decisions and prescribe therapy in a personalized and sustainable manner, balancing therapeutic efficacy with the patient’s daily needs and difficulties, but the use of wearable sensors is poorly investigated.

“Wearable sensors are available that objectively monitor the brace-wearing time, but their use, combined with other interventions, is poorly investigated.- explains prof. Stefano Negrini, ISICO Scientific Director and one of the authors of the research – We conducted a systematic review of the literature published (466 articles and included examples articles) to summarize the real compliance with bracing reported by studies using sensors; to find out the real brace wearing rate through objective electronic monitoring; to verify if interventions made to increase adherence to bracing can be effective according to the published literature”. 

The research Personal and Clinical Determinants of Brace-Wearing Time in Adolescents with Idiopathic Scoliosis‘ performed a cross-sectional study of 514 adolescent patients consecutively recruited in the last three years at a tertiary referral institute and treated with braces for one year.

“Some studies investigated adherence determinants but rarely through sensors or in highly adherent cohorts – tells Dr. Giulia Fregna, one of the authors of the research  – We aimed to verify the influence of personal and clinical variables routinely registered by physicians on adherence to brace treatment in a large cohort of consecutive AIS patients from a highly adherent cohort. We have identified gender, age (considered alongside bone age), and the “bracing hours prescription” as critical determinants of adherence behaviour. These findings underscore the importance of tailoring interventions to address the specific needs of different patient populations”.