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Scoliosis: why choose rehabilitation treatment?

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I have scoliosis. What should I do? Do I absolutely have to follow a treatment, or is there no point? Will I need to be operated on? These are questions we often get asked by patients who have been diagnosed with scoliosis.

Therapeutic approaches to scoliosis fall into two categories: surgical treatment, indicated only in a limited number of cases, and conservative treatment, which we prefer to call rehabilitation treatment. This latter category comprises different approaches, which are based on the severity of scoliosis. 

First of all, there is simple clinical observation (for very mild cases), then treatment based on specific self-correction exercises (for mild scoliosis), and finally bracing (for the treatment of moderate forms). The braces used can be elastic, rigid or super-rigid. The choice of brace type and the number of prescribed brace-wearing hours (treatment dose) are always determined by two key factors: the severity of the curve(s) and the risk of worsening.

Even though surgical techniques have improved enormously over the years, surgery for scoliosis always entails vertebral fusion, and thus a complete loss of mobility (function) of the section of the spine involved, which is transformed into a single bone. It is the most difficult surgery in orthopaedics (apart from surgery for severe poly-trauma), and naturally it carries all the risks that derive from the fact that the spine encases and protects the spinal cord, which contains all the connections between the brain and the lower limbs.  

Rehabilitation treatment, therefore, must always be considered the first-choice treatment for scoliosis. This even applies to “surgical curves” (i.e., those with a Cobb angle greater than 45°–50°), if no attempt has ever been made to correct them through full-time bracing and specific exercises (1). In short, surgical treatment is used only when rehabilitation treatment has failed.

What are we aiming to achieve through rehabilitation treatment?

Basically, we are aiming to obtain a back that is not only strong and efficient but also aesthetically pleasing. This is, indeed, one of our main objectives, given that a person’s quality of life is strongly influenced by how they see themselves physically. Therefore, a brace needs to be built in such a way as to reduce the external deformity as well as the magnitude (i.e., the Cobb degrees) of the curve(s). In this regard, it is very important to underline the importance of preventing scoliosis from worsening, especially in puberty when it is at the greatest risk of doing so. Reducing the Cobb degrees of a scoliotic curve is always an objective, but given that scoliosis in puberty almost always worsens unless it is treated properly, simply blocking the evolution of the condition must, in itself, be considered a successful result.

Through rehabilitation treatment, we also try to prevent the onset of back pain in adulthood. To this end, as well as treating any pain that occurs in childhood and adolescence, we also do our best to preserve, as far as possible, the physiological curves present in the sagittal plane. Several studies have shown that back pain in adults with scoliosis is highly correlated with abnormalities in the sagittal plane, even more so than with scoliotic curve magnitude (2). And unfortunately, over the years, scoliosis that exceeds certain levels tends to progressively worsen; as a result, for purely mechanical reasons, the trunk progressively falls forwards.

Finally, rehabilitation treatment aims to prevent the respiratory system problems that can arise due to progressive deformation of the rib cage in the presence of a severe thoracic curve.

All these objectives were extensively discussed, and identified as therapeutic priorities, by international experts from the International Society on Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT) during the drafting of the SOSORT Guidelines (3). 

(1) Lusini M, Donzelli S, Minnella S, Zaina F, Negrini S. Brace treatment is effective in idiopathic scoliosis over 45°: an observational prospective cohort controlled study. Spine J. 2014 Sep 1;14(9):1951-6. doi: 10.1016/j.spinee.2013.11.040. Epub 2013 Dec 1. PMID: 24295798.

(2) Diebo BG, Shah NV, Boachie-Adjei O, Zhu F, Rothenfluh DA, Paulino CB, Schwab FJ, Lafage V. Adult spinal deformity. Lancet. 2019 Jul 13;394(10193):160-172. doi: 10.1016/S0140-6736(19)31125-0. Epub 2019 Jul 11. PMID: 31305254.

(3) Negrini S, Donzelli S, Aulisa AG, Czaprowski D, Schreiber S, de Mauroy JC, Diers H, Grivas TB, Knott P, Kotwicki T, Lebel A, Marti C, Maruyama T, O’Brien J, Price N, Parent E, Rigo M, Romano M, Stikeleather L, Wynne J, Zaina F. 2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth. Scoliosis Spinal Disord. 2018 Jan 10;13:3. doi: 10.1186/s13013-017-0145-8. PMID: 29435499; PMCID: PMC5795289.

Conservative or surgical treatment in adults? Two steps of therapy

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Is there an alternative treatment to another in adults with scoliosis who suffer from back pain? The answer is no, simply because therapy is made up of several steps. 

It just has been published by the scientific journal Annals of Translational Medicine the editorial comment of Isico “Symptomatic adult spinal deformity: implications for treatment“. A comment to another editorial, namely “Operative Versus Nonoperative Treatment for Adult Symptomatic Lumbar Scoliosis” which compared the treatment for adults with conservative asymptomatic scoliosis with that for surgical scoliosis.

Let’s start with a premise.

Lumbar scoliosis is particularly relevant for its significant correlation with back pain. There are two main common etiologies for this pattern, degenerative scoliosis and idiopathic. Degenerative curves, also called “de novo” scoliosis, derives from pathological changes at the level of the facet joints and discs in the lumbar spine. Usually, they are not very large but frequently very painful and rapidly progressive. The other type is idiopathic scoliosis appeared during growth that starts its progression in adulthood, usually depending on the size of the curve as previously stated. There is a further type of adult scoliosis called metabolic, which is less frequent.

The most common treatment for scoliosis patients with chronic low back pain, according to current practice, is the surgical one. This has the aim of both preventing progression and improving pain and quality of life. Unfortunately, surgery in such patients is associated with a relevant number of complications, so that it cannot be considered appropriate for every patient. Moreover, some patients don’t want to be operated.

“The study we considered – explains Dr Francesca di Felice, physician of Isico – presents a mixed design, with a randomized and an observational arm. In both arms, conservative treatment was compared to surgery. The general conclusions were driven from the observational arm, since in the randomized one the rate of crossover was dramatically high (64%): this led to similar results for both the approaches in the intent to treat analysis (ITT). For the observational arm, the success of surgery in improving pain and reducing disability was clearly higher than for the conservative approach as supported by the as-treated analysis. We think that this study raises a number of interesting points that should be discussed in the scientific community. The authors tried to apply the best possible design, which is the randomized control trial, but its results were not really informative for the high crossover rate. Hence our comment.”

The ITT is considered more conservative in such cases, and this could be an advantage in case some efficacy is equally demonstrated, but it also underestimates the side effects, and this is a significant shortcoming. We think it’s thus evident that the RCT design cannot be applied to the comparison of surgery and conservative treatment at least in this specific field of spine care. When patients have to face big issues like painful scoliosis, and/or very invasive treatments like fusion for scoliosis, they want to choose their treatment. Some of them want to be operated in case the conservative treatment is not effective, and others are scared of surgery and decide to avoid it. 

Another limitation of the study is that there was no distinction between degenerative and idiopathic scoliosis. We know that the progression rate of the two is different, and also the association with pain. Degenerative scoliosis is more challenging for the conservative treatment, and focusing on this would have been more informative.

Furthermore, the most severe surgical complications for the patient compared to conservative exercise and brace treatment were not considered in the study.

“We are convinced that the choice between one treatment or another cannot be an alternative and thus dichotomous – concludes Dr Di Felice – both treatments must be considered as a step of therapy, if conservative treatment is not sufficient, it is necessary to resort to surgery.

 Surgical complications are a big challenge in adult patients with scoliosis, so we cannot consider surgery as the best option for a problem that can affect QoL but is not life-threatening. We strongly believe that surgery can be a good option for very selected and motivated patients, but we need more data about the advantages of a surgery over the conservative treatment, and hopefully a further improvement of the surgical approach. On the other side, the conservative treatment protocol applied in this study doesn’t rely on the Guidelines on the conservative treatment currently available, we need an appropriately conservative approach to be studied, based on the current guidelines and evidence and managed by experts in the field.”