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Artificial Intelligence: A Revolution in Rehabilitation?

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Artificial Intelligence (AI) is transforming the way medical professionals approach rehabilitation, offering innovative tools that enhance the quality of treatment. At ISICO, we are increasingly committed to exploring how AI can support daily clinical work and contribute to highly personalised therapeutic decisions.

We discussed this with Francesco Negrini, a specialist physiatrist at ISICO and the author of a groundbreaking 2023 study on AI and rehabilitation. This study, titled “Developing a new tool for scoliosis screening in a tertiary specialist setting using artificial intelligence: a retrospective study on 10,813 patients,” won the prestigious SOSORT Award in 2023.

Dr Negrini recently presented another paper exploring the use of AI in rehabilitation projects, particularly in stroke recovery.

What Are the Key Areas Where AI Can Be Used in Rehabilitation?
Artificial Intelligence (AI) is incredibly versatile and can be applied at various stages of the medical process, ranging from diagnosis, using automated analysis of X-ray or MRI images to identify pathologies with greater precision, to prognosis, with predictions on treatment outcomes, and on to the personalisation of treatments, determining the most effective therapeutic pathway based on patient data. AI also enables continuous monitoring, allowing real-time evaluation of a patient’s progress to adapt the treatment accordingly.
At ISICO, we are exploring, for example, how AI can support personalised treatment approaches. This technology could analyse a patient’s natural history and the likelihood of success when using one type of brace over another, providing physicians with more accurate decision-making tools.

Can you give a concrete example of how ISICO is using AI?
A significant example is the research that won the SOSORT Award 2023, recently published (link). The study demonstrated how analysing clinical data using advanced techniques can enhance our understanding of scoliosis and its treatments.

Another potential application involves the diagnosis of low back pain, where AI can analyse radiographic images to identify aetiologies that might otherwise be missed by the human eye. This approach takes advantage of today’s enhanced computational power, enabling the rapid and accurate processing of large volumes of data.

How Could AI Transform the Management of Spinal Disorders in the Future?
There are three key areas where we see tremendous potential. The first is screening and early diagnosis, which involves detecting scoliosis or other conditions at an early stage to improve treatment outcomes. The second area is the customisation of braces, using data collected from clinical centres to predict which type of brace will be most effective for a specific patient. Lastly, monitoring outcomes plays a crucial role, as it allows for tracking the progress of therapy and adapting it based on observed improvements, thereby enhancing the overall effectiveness of treatment.

What Makes AI Such a Valuable Ally for Clinicians?
AI amplifies a clinician’s capabilities, providing more detailed information and helping them make data-driven decisions. However, as we always emphasise at ISICO, the doctor-patient relationship remains central. AI does not replace the experience and empathy of a clinician; instead, it offers tools that enhance human expertise.

What is the Future of AI in Rehabilitation Medicine?
I believe we will see an increasingly close integration of AI in clinical practice. At ISICO, we are moving in this direction, exploring how AI can improve therapeutic outcomes and make rehabilitation more targeted. We are just at the beginning, but the possibilities are immense, especially if we can combine the best of technology with the invaluable expertise of healthcare professionals.

Free Pelvis Brace works: this is demonstrated by the study presented at Sosort

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At the latest Sosort international conference, held a few months ago, Isico presented the study Increasing Brace Comfort, Durability and Sagittal Balance through Semi-rigid Pelvis Material does not change Short-Term Very-Rigid Sforzesco Brace Results.
For years, Isico has replaced plaster cast with the Sforzesco brace, a particular type of very rigid brace for the most demanding scoliotic curves: developed in the Institute itself in 2004, it obtained results equal to casting, highlighted in several published studies.
The Sforzesco brace is a way to avoid casting for severe curves, because of the significant costs involved both at the individual (side effects including cast syndrome, skin problems, significant psychological impact, inability to shower for months, etc.) and social (repeated inpatient treatments) levels.
“In recent years, thanks to the experience with the Sforzesco brace, we have worked to improve our brace – explains dr Francesco Negrini, physiatrist, and one of the authors of the research presented at Sosort – We have therefore recently introduced a particular innovation, the system “Free Pelvis”, which consists of releasing the pelvis corset using a less rigid material at that level, increasing comfort while wearing. The “Free Pelvis” system is a very important innovation, a potentially big step forward in conservative treatment of scoliosis”.
The study presented compared the Sforzesco brace classical version (VRB) versus the Free Pelvis one (FPB): “The results obtained showed us that the Sforzesco “Free Pelvis” has no inferior results to the classic Sforzesco – concludes dr Negrini – furthermore it reassures the effectiveness of the Sforzesco “Free Pelvis”, and allows us to continue with greater confidence and conviction in the process of introducing this new and revolutionary instrument into our regular clinical practice”.

Scoliosis: is aesthetics measurable?

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When it comes to scoliosis therapy, aesthetics is one of the goals along with a healthy back.

Aesthetic deformity due to scoliosis and its impact on the patient is considered by the members of SOSORT (International Society On Scoliosis Orthopaedic and Rehabilitation Treatment) as the most important reason for treating AIS; unfortunately, only a few of scoliosis studies were found in PubMed on this topic. 

But can a goal, apparently so subjective, be measurable in a repeatable way to become objective? Yes,according to the data collected by the study Reliability, repeatability and comparison to normal of a set of new stereophotogrammetric parameters to detect trunk asymmetries, recently published by the Journal of BIOLOGICAL REGULATORS & Homeostatic Agents. 

“Aesthetic impairment is a crucial issue in Adolescent Idiopathic Scoliosis (AIS), but to date no objective measurements are available – states Dr Francesco Negrini, Isico physiatrist – for our research, we used the Formetric®, which we usually use to measure sagittal planes. We have established parameters for evaluating symmetries in patients, such as those of the shoulder blades or hips, to obtain objective data related to the aesthetic aspect. In order to validate this instrument for clinical practice, the first step and aim of this study are to evaluate the repeatability of the parameters measured by surface topography in a group of AIS subjects and to test if they can distinguish healthy subjects from AIS patients to develop an objective tool for deformity evaluation of the trunk in AIS patients. For our evaluations, we used a device for surface topography based on the principles of rasterstereography. This device (Formetric®, Diers Biomedical Solutions) can reconstruct digitally in three dimensions the back of any person”.

The study evaluated 15 selected parameters that could be good predictors of scoliosis’ impact on the patients’ trunk.
“We analysed short-term (30 seconds, 38 subjects) and medium-term (90 minutes, 14 subjects) repeatability of surface topography measures and their diagnostic validity in AIS (74 subjects, 33 AIS patients and 41 healthy subjects) – proceeds Dr Negrini – All examined parameters were highly correlated as far as short, and medium-term repeatability is concerned”. 

When it comes to aesthetics we cannot stop at Cobb degrees alone, believing that there is no objective measure: “Symmetries can be measured repetitively, as we did in our study – concludes Dr Negrini – so we can offer an objective measurement of aesthetics in patients with idiopathic scoliosis. The surface topography showed good repeatability. Moreover, some of its parameters are correlated with scoliosis, showing that it could very well evaluate deformity due to this pathology. Thanks to these findings, it will be possible to develop a tool that can objectively evaluate aesthetics in AIS patients.”.